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|Facility:||Children's Hospital Oakland Research Institute|
***This position is contingent upon external funds***
This position is in both the Center for Genetics and the Center for the Prevention of Obesity, Cardiovascular Disease & Diabetes. The purpose of the position is to support a cutting-edge pharmacogenomics research project focused on investigating the genetic and molecular determinants that contribute to human variation in statin drug response. The results of this research could yield significant improvement in the ability to identify those individuals most likely to achieve cardiovascular benefit from statin treatment, as well as investigate the potential future use of statins in the treatment of cancer.
Experimental laboratory procedures include preparation of next generation sequencing libraries (including transcriptome and microRNA sequencing), qRT-PCR, tissue culture, nucleic acid extractions from cultured cells and primary human and/or mouse tissue, Western blots, FACS, GC/MS, microscopy, bacterial cloning, lipid characterization. Position also requires some housekeeping duties, supplies ordering and preparation/maintenance of common-use reagents, buffers, and equipment.
Initiative and scientific engagement are exceedingly valued within this particular laboratory workplace community. The position allows for attendance at the CHORI Faculty Seminar Series, Children’s Hospital Oakland Grand Rounds, monthly seminars given by visiting scientists, and on-site journal clubs in a variety of disciplines. The employee with exceptional leadership abilities and work ethic will also have the opportunity to present their project progress to the CHORI scientific community via slide presentation and/or poster session. For the highest caliber employee, mentorship and opportunities to contribute to projects leading to abstract submission at national scientific conferences and journal publication are available. The position affords numerous additional opportunities for career growth, workplace education, and advancement.
POSITION REQUIREMENTS: Minimum Education and Experience: 1-2 years of college including courses in the natural sciences or graduation from high school. Knowledge/Skills: Ability to achieve a basic understanding of routine laboratory procedures or have the ability to be trained. Previous experience leading independent research and/or completion of a bachelor’s level honors research project using the basic techniques or methods required in the position. Ability to learn new laboratory procedures quickly, troubleshoot protocols, and think creatively both independently and as a team to efficiently solve problems. Strong academic record. Outstanding oral and written communication skills and willingness to contribute enthusiastically to weekly lab meetings, share ideas, and offer and receive constructive feedback on experimental approaches.Reliable, diligent, meticulous and will take initiative in maintaining an organized laboratory environment and detailed records of tasks performed. Macintosh/PC computer experience, especially Microsoft Excel. Additional computational skills are looked upon highly favorably
PHYSICAL REQUIREMENTS: Sit: Up to 8 hours/day Stand/Walk: Up to 6 hours/day Bend/Stoop: Up to 6 hours/day Reach: Up to 6 hours Rep Use of UE/Grasp: Up to 8 hrs Lift/Push/Pull: 25lbs, over 25# with assistance or equipment This job requires the ability to hear alarms clients and/or instruction. The ability to see accurately from 20 inches to 20-ft. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential function of this position.