· Solid programming skills in R, Python or another high level programming language · Expert in NGS (research and clinical) pipeline analyses, including BWA, GATK, Mutect, Tophat2, STAR, Cufflinks, and tools for detection of gene fusions, calling structural variations and inference of copy number variations · Knowledge and experience of Unix/Linux, proficient in shell command scripting · Deep understanding of genomic annotation databases and data formats: ANOVAR, ClinVar, PolyPhen, SIFT, dbSNP, 1000 Genome, refSeq, Ensembl gene annotations and SAM/BAM, BED, MAF, VCF, WIG, GFF/GTF file formats · Extensive expertise on QA/QC tools such as FASTQC, QC3, RSeQC and components of GATK · Capability of implementing customized scripts internally for extensive QC measurements · Expert knowledge on other widely used NGS data processing tools such as samtools, bedtools, bamtools etc · Experience working in a cloud based, high performance computing environment · Knowledge of public databases (e.g. TCGA, ICGC, cBioPortal) and data visualization tools (e.g., IGV, UCSC genome browser) · Willingness and ability to learn new skills quickly · Passion for science and oncology · Strong leadership skills coupled with the ability to lead and influence cross-functional, cross-company teams as we establish new capabilities. · Ability to work effectively in a team environment with research scientists, biotech/pharma, cancer center IT/informatics personnel, data managers, programmers, and statisticians · Excellent communication and networking skills · Capability to select or deselect individuals with the appropriate collaborative mindset · Ability to handle numerous complex internal / external relationships at a time · Ability to understand and appreciate needs and perspectives of the stakeholders/partnerships · Ability to recognize and constructively address problems and conflicts · Demonstrated ability to engage in effective joint problem-solving to address key working together challenges · Knowledge of FDA/ICH guidelines and industry standard practices regarding the management of clinical trial data standards · Working knowledge of global regulatory requirements regarding data standards · Some travel may be required Experience and Credentials: · Ph.D. in Bioinformatics of related field · 10+ years of experience post Ph.D · Experience in clinical NGS pipeline analysis |